It's about hippocampal size, so people with a larger hippocampus are less likely to get alzheimers as it's a barrier, lots of studies scanning London cabbies brains and they have enlarged hippocampus - it's believed to give a barrier against alzheimers.
So spatial navigational ability is another risk factor/biomarker (along with blood pressure, smoking etc)
"Video gaming, but not reliance on GPS, is associated with spatial navigation" paper shows there was a significant association between self-reported weekly hours of video gaming and wayfinding performance.
So spatial navigational ability is another risk factor/biomarker (along with blood pressure, smoking etc)
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