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Digital pathology are just a lot bigger than radiology, we regularly see slides 500k x 500k pixels.


Yes, they can be huge, and for modalities like multiplex immunofluorescence with up to 20 channels, you're often dealing with very faint proteomic signals. Preserving that signal is critical, and compression can destroy it quickly.


CODEX can do up to 120 channels I think. They are also 16/32bit. They are usually just deflated


I find it funny that car discussions here are so much busier than computer discussions. I wonder if over there at the mechanics forum they spend as much time discussing their laptops and ignoring the drills and screwdrivers


It's because people have a bone to pick and aren't actually invested in the car industry


Even Albania such a US-liking country! or Jordan!


Yep, someone was bragging recently they used 13B tokens last year. At 8mg CO2/token that's ~100t of CO2. Consumption of 5 households (or 200 NYC-London flights) just for vibe coding!


Hey! Don't you dare to compare SQL and CSS. SQL is not a cobbled together mess of incremental updates with 5 imperfect ways of achieving common tasks that interact in weird ways. Writing everything in SQL-92 in 2026 is not gonna get you weird looks or lock you out of features relevant for end users. If writing SQL for your problem feels difficult it's a good sign you ought to look at alternatives (eg. use multiple statements instead). Writing the right CSS being difficult is normal.


> Don't you dare to compare SQL and CSS. SQL is not a cobbled together mess of incremental updates with 5 imperfect ways of achieving common tasks that interact in weird ways.

Reminds me a little bit of Sascha Baron Cohen's democracy speech [1] in The Dictator ;-)

Both SQL and CSS have evolved through different versions and vendor specific flavors, and have accumulated warts and different ways to do the same thing. Both feel like a superpower once you have mastered them, but painful to get anything done while learning due to the steep learning curve.

[1] https://www.youtube.com/watch?v=XUSiCEx3e-0


Give it time reprogramming stem cells without the source code or even disassemblers is hard


That's not that early, no? There was probably enough C, H, N, O, P, S, Na atoms for life to start 10B years ago. You probably couldnt rely on iron being everywhere though but that's not such a hard requirement.


It's fascinating to ponder, for sure.

The universe still has plenty of time to burn, especially red dwarfs. It's sad to think about starless skies, though.

The heme is pretty magical. Probably not a hard requirement, but it sure has been useful for us here.


I love the Chad: "I love you!" c15: (oil and engine lights on) "Please let me die"



Please just make SmartTVs unattractive and force companies to make dumb TVs again Please just make SmartTVs unattractive and force companies to make dumb TVs again Please just make SmartTVs unattractive and force companies to make dumb TVs again


Just buy "digital signage"


Which works, but is priced very high - and not just for the fact that the seller can't monetize ads. Digital signage displays are designed for much higher duty cycles than a home TV, for display in areas where ambient brightness is much higher on average. You're paying for the tech that you want, but you're also paying for a lot of tech that you don't want or need.


Right, but what everyone is whingeing about is for it to be available even at a higher price point.

Digital signage shows the market is already solving this problem so if all this complaining is to mean anything people are talking about yet another new market that fits in between the smart TV price and the digital signage price


Oh! I thought it's going to be about some interesting topology of nut shell...


Likewise, I'd assumed sphere eversion: https://en.wikipedia.org/wiki/Sphere_eversion


That's ... concerning.


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