Yes and no. RetroPie can run SNES games using comparatively inaccurate emulators (SNES 9x, ZSNES; mostly sound bugs), but can’t run more accurate emulators like Higan acceptably.

RetroPie (or libretro) does not have a ZSNES core; ZSNES, apart from being wildly inaccurate, is largely written in x86 assembly and so there is no ARM version.

Additionally, the more modern snes9x cores have essentially the same sound emulation as higan (blargg's SNES_SPC library). I believe higan has done some modification of that code since importing it but regardless, the sound emulation in snes9x is very, very accurate.

Higan is indeed unparalleled for those who truly care about extreme accuracy, but snes9x is 99% there for the vast majority of users who just want to play games.

True but that sort of is the issue with things like Higan - proper CPU architecture emulation is REALLY slow in software.

The op said effectively, not perfectly.