Most medium sized, and above, dogs could bite your hand off no problem.

Ya’d need to keep them in an enclosure. They breed in captivity fine.[1]

I wonder if they could be bred to become house pets. Could take a while.

1. http://theconversation.com/tasmanian-devils-reared-in-captiv...

They are infamously aggressive. There is ongoing debate about the wisdom of keeping extremely aggressive dogs as pets, so the dog comparison isn't really a good rebuttal.