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This news story raises several big red flags.

This story was reported by Laura Ingraham on Fox News. Her tweet promoting this as a "cure" was immediately withdrawn by Twitter as "misleading". The 40 minute video interview with Zelenko, again on Fox News, was conducted not by a medical reporter, but by Rudy Giuliani. Zelenko goes on to make numerous huge dire public health predictions -- none of which a family practitioner has any business suggesting, especially in public on a national news outlet.

As always, consider the source of the information.

It's also very important to note that Zelenko was treating 700 unhospitalized patients; these were not cases severe enough to admit to a hospital. He treated them from his home (since he lost a lung to cancer years ago). So he never actually physically met with any of those 700 patients to monitor their progress.

In fact it's likely that many of these patients never tested positive, but simply self-reported as positive, further diluting the 'trial'.

And because 80% of positive COVID-19 cases are minor or even asymptomatic, the number of his patients that really _needed_ treatment falls from 700 down to, at most, 140 (20% of 700). That's a much smaller treatment effect that a large number like 700 would suggest.

It's also important to note that, apparently, Dr Zelenko treated sick people with medications that were NOT approved for the target disease. And he did so apparently without approval from any higher public health authority. In short, it appears that he experimented on his patients without authorization to do so from a public health or research authority.

Zelenko is a family medicine doctor, not a specialist in infectious disease or research. Thus it's very unlikely he wrote up an experimental design with proper safeguards, much less got it approved. With such poor experimental controls, it's impossible to interpret his results. What's more, if any of his patients later incur harm (like heart attacks from the chloroquine), such a laissez-faire approach to medicine will invite lawsuits galore.

No. Anecdotal evidence alone is NEVER enough.



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