Another thing you might not realize is that Mac spacebars are narrower, which puts the command keys closer to the center of the keyboard where they can more easily be reached using thumbs. Alt on a PC keyboard is harder to reach than Command on a Mac keyboard.
I think it's because ctrl+z and ctrl+y are easy to press, while cmd+y is hard to press because of the bad placement of the cmd key.
> Option-Command-Esc (from the link)
I would like to see how you press this combo with your left hand only, Alt+F4 is not ideal but much easier if I raise my left elbow away from my body.