Interesting. I adore God Emperor, but I feel as if it's lightest on plot of all six books. In any case, I love the plot device of Leto's Stolen Journals as a way for Leto/Frank to expound philosophically on themes of religion, government, and nature. That book is an embarrassment of riches when it comes to stimulating observations.
As far as the Villeneuve films go, my sincerest wish is that we can somehow make it to a God Emperor film. I have no idea what this would look like, or if it would be any good, but I'll keep dreaming.
Now I’m halfway through Heretics and I believe the last 3 books would make an excellent dialogue-heavy anime. Very hard to see them as widely popular films.
As far as the Villeneuve films go, my sincerest wish is that we can somehow make it to a God Emperor film. I have no idea what this would look like, or if it would be any good, but I'll keep dreaming.