Generally, yes, and tanks usually roll with air support if not also infantry. Russia's neglect of this armchair-strategist type knowledge is making headlines.
Tanks without infantry support are basically just targets. Especially in urban environments, the Turkish army showed that quite impressively in Syria (?) by loosing a couple of Leopard 2s.
The Russians supposedly had a tank chassis with soft weapons ( machine guns, small cannon, grenade launchers) on top, to accompany tanks in urban environments, specifically due to lessons from Checnhya about the vulnerability of tanks against infantry defenses, especially in urban environments - BMPT. Supposedly the idea was to have them accompany tanks and support them. In reality, they are nowhere to be seen
BMPTs were seen heading into theater on railcars. I've seen nothing since, but I suspect they're out there somewhere.
I also suspect they would fare little better than a lone T-80 wandering around an urban environment without competent infantry support. Also, BMPT was designed around the Grozny threat environment: antiarmor teams on rooftops raining down RPGs and Molotov cocktails from above. The Ukrainians haven't been forced to resort to those tactics (yet) as they have advanced Western weapons to employ from greater distances and with greater lethality.
