Diablo 2 drifts pretty far from the formula, to the extent that it largely defines the "action RPG" genre as we still know it.
my credentials: I'm the creator of what I think was the world's first commercial-only, traditional Rogue-like game (AFAIK)
Rogue and then its Rogue-like descendents: Hack, NetHack, Angband, Dwarf Fortress, DCSS etc