Microsoft Sculpt Ergo keyboard in standard QWERTY, without the numpad (so the mouse can sit naturally next to it). It has soft laptop keys, the opposite of a mechanical keyboard. Used it for more than a decade and can comfortably type for hours at around 130wpm.
I used to have really bad hand cramps and this saved my hands (and probably my career). Best keyboard I've ever had, by a large margin (both ergo and not, mechanical and not).
It's not made out of any fancy materials, but it's held up for years without issue for me.
I use a Magic Mouse for work because it's the only thing I can click repeatedly without pain (using my pointer and middle finger together to left click is a lot easier than the pointer finger, over decades).
For gaming I use a SteelSeries Rival 3 Wireless. It works great and is light.
I used to have really bad hand cramps and this saved my hands (and probably my career). Best keyboard I've ever had, by a large margin (both ergo and not, mechanical and not).